Prof. Park's biography, personal activities and awards. Read More
Targeted Protein Upregulation of STING for Boosting the Efficacy of Immunotherapy. Cho, W.†; Won, S.†; Choi, Y.; Yi, S; Park, J.B.; Park, J.-G.; Kim, C.E.; Narayana, C.; Kim, J.H., Yim, J. Choi, Y. I. Lee, D.-S.*; Park, S.B.*; Angew. Chem. Int. Ed. 2023, e202300978. (DOI: 10.1002/anie.202300978) (IF: 16.823)
Inhibition of ACE2-Spike interaction by ACE2 allosteric binder suppresses SARS-CoV-2 entry. Shin, Y.-H.†; Jung, K.†; Lee, J.; Lee, H.J.; Kim, J.; Kim, S.*; Park, S. B.*; Angew. Chem. Int. Ed. 2022, 61, e202115695. (DOI: 10.1002/anie.202115695) (IF: 16.823)
Host immunomodulatory lipids created by symbionts from dietary amino acids. Oh, S.F.†*; Praveena, T.†; Song, H.B.; Yoo, J.-S.; Jung, D.-J; Erturk-Hasdemir, D.; Hwang, Y.S.; Lee, C.C.; Nours, J.L.; Kim, H.; Lee, J.; Blumberg, R.S.; Rossjohn, J.*; Park, S.B.*; Kasper, D.L.* Nature 2021, 600, 302–307. (DOI: 10.1038/s41586-021-04083-0) (†: equally contributed) (IF: 69.504)
Phenotypic Discovery of Neuroprotective Agents by Regulation of Tau Proteostasis via Stress‐Responsive Activation of PERK Signaling. Shin, Y.-H.; Cho, H.; Choi, B.Y.; Ha, J.; Kim, J.; Yim, J.; Suh, S.W.; Park, S. B.* Angew. Chem. Int. Ed. 2021, 60, 1831–1838. (Cover article) (IF=12.959)
Nature-inspired remodeling of (aza)indoles to meta-aminoaryl nicotinates for the late-stage conjugation of vitamin B3 to (hetero)arylamine therapeutics. Varun, B.V.†; Vaithegi, K.†; Yi, S.; Park, S. B.* Nature Communications 2020, 11, 6308. (†: equally contributed) (IF=12.121)
Label-free target identification reveals oxidative DNA damage as a mechanism of selective cytotoxic agent in cells with downregulated mismatch repair pathway. Park, H.; Park, S. B.* Chem. Sci. 2019, 10(12), 3449–3458. (IF=9.063)
Divergent Synthetic Pathway for Pyrimidine-Embedded Medium-Sized Azacycles through N-quaternizing Strategy. Choi, Y.†; Kim, H.†; Park, S. B.* Chem. Sci. 2019, 10(2), 569–575. (IF=9.063)
Monochromophoric Design Strategy for Tetrazine-based Colorful Bioorthogonal Probes with a Single Fluorescent Core Skeleton. Lee, Y.; Cho, W.; Sung, J.; Kim, E.*; Park, S. B.* J. Am. Chem. Soc. 2018, 140(3), 974-983. (Selected as Cover Article). (IF=13.858)
Label-Free Target Identification Using In-Gel Fluorescence Difference via Thermal Stability Shift. Park, H.; Ha, J.; Koo, J.Y.; Park, J.; Park, S.B.* Chem. Sci. 2017, 8(2), 1127-1133. (IF=9.144)
Diversity-Oriented Synthetic Strategy for Developing Chemical Modulator of Protein–Protein Interaction. Kim, J.†; Jung, J.†; Koo, J.; Cho, W.; Lee, W. S.; Kim, C.; Park, W.; Park, S.B.* Nature Communications, 2016, 7, 13196. (IF=11.329)
Discovery of small-molecule inhibitors of protein–microRNA interaction using a high-throughput binding assay with a site-specifically labeled Lin28. Lim, D.; Byun, W.G.; Koo, J.Y.; Park, H.; Park, S.B.* J. Am. Chem. Soc. 2016, 138, 13630-13638. (IF=13.038)
β-Turn Mimetic-based Stabilizers of Protein-Protein Interactions for the Study of the Non-canonical Roles of Leucyl-tRNA Synthetase. Kim, C.†; Jung, J.†; Tung, T.T.; Park, S.B.* Chem. Sci. 2016, 7, 2753-2761. (IF=9.211)
Rational Improvement of Molar Absorptivity Guided by Oscillator Strength: A Case Study with Furoindolizine-based Core Skeleton. Lee, Y.; Jo, A.;Park, S.B.* Angew. Chem. Int. Ed. 2015, 54(52),15689-15693. (IF: 11.336).
Discovery, Understanding, and Bioapplication of Organic Fluorophore: A Case Study with an Indolizine-Based Novel Fluorophore, Seoul-Fluor. Kim, E.; Lee, Y.; Lee, S.; Park, S.B.* Acc. Chem. Res. 2015, 48(3), 538–547. (IF: 24.348)
Park, J.; Oh, S.; Park, S. B.*Angew. Chem. Int. Ed. 2012,51(22), 5447.
방사형 형광 화합물, 그 제조방법 및 그의 이용. 박승범, 김은하, 고민섭, 류지훈; 국내출원 (2008.04.29) 출원번호 (10-2008-0039873)
Advanced Fluorescence Reporters in Chemistry and Biology I, Kim, E.; Park, S.B.* Springer, 2010, 8, 149–186.
Professor, Researchers, Students and Alumni
Sciecne and technology medal of honor, Korean Government
2023 과학정보통신의날 기념
과학기술포장 수상
Reserach excellency award, Seoul National University
서울대학교 학술연구상 수상
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